One of the most common ailments chickens can suffer is coccidiosis. Coccidia are parasites on chickens, which infect the chicken’s stomach tissue upon ingestion. Once attached to the tissue, the organism starts to multiply and spread. In severe cases, this will cause bleeding within the intestinal tract or cecal, which starts to have a negative impact on the animal’s health. If left untreated, coccidia can be fatal. Smart backyard chicken keepers keep Amprolium on hand and use as it as a preventative measure against this fatal illness.

Amprolium is a coccidiostat (antiprotozoal) used for the treatment and prevention of coccidiosis in calves, sheep, goats, chickens (broilers and breeders) and other fowl such as turkeys, with activity against Eimeria spp., especially Eimeria tenella and Eimeria necatrix. It is a thiamine (vitamin B1) analogue and its pharmacological effect relies on competitive inhibition of thiamine uptake. Amprolium competitively inhibits the active transport of thiamine in isolated second-generation schizonts of Eimeria spp. and in host intestinal cells. Upon ingestion of amprolium, the coccidia experience thiamine deficiency and starve from malnutrition.


Amprolin-300 WS is indicated for coccidiosis caused by coccidia susceptible to amprolium (Eimeria spp.) or gastrointestinal infections for which it is therapeutically or prophylactically indicated to administer amprolium in calves, goats, sheep and poultry. Amprolium 250 wsp is a concentrated powder of Amprolium HCl, water-soluble for use in drinking water of poultry, calves, lambs, young goats, cattle and sheep. It is used as a preventive or therapeutic agent against Eimeria infections in poultry, especially E. tenella, E. necatrix, E. acervulina and E. praecox.

It is effective against other protozoal infections like Histomoniasis (Blackhead) in turkeys and poultry; against coccidiosis in calves, sheep and goats; against amaebiasis in various species.

Dosage And Administration:

For oral administration via feed or drinking water.

  • Poultry : 100 – 150 g per 100 litres of drinking water during 5 – 7 days, followed by 25 g per 100 litres of drinking water during 1 or 2 weeks. During treatment medicated drinking water should be the only source of drinking water.
  • Calves, lambs, kids : 3 g per 20 kg bodyweight as drench during 1 – 2 days, followed by 7.5 kg per 1,000 kg of feed during 3 weeks.
  • Cattle, sheep : 3 g per 20 kg bodyweight during 5 days (via drinking water).

Mixed with feed, the product should be used immediately. Medicated drinking water should be used within 24 hours.
If no improvement is noted within 3 days, evaluate the symptoms to determine the presence of other diseases. Follow the instructions of your veterinarian or poultry pathologist.

Brands of Amprolium

.These include: CORID 20% Soluble Powder – (United States) Can be given as a 21-day preventative or a 5-day treatment. It is mixed into the flock’s water source. There is 200 mg of amprolium in every 1 gram of this medication. CORID 9.6% Oral Solution – (United States) This product is available as a 1 gallon or 16 oz bottle. Can be given as a 21-day preventative or a 5-day treatment. It is mixed into the flock’s water source. There are 96 mg of amprolium in every 1 mL of CORID 9.6% Solution. Amprolin-300 WS – Comes as a water-soluble powder and mixed into the drinking water. It can be given as a preventative or treatment. For prevention, it is given at 1 kg per 5000 L of water, for 1-2 weeks. As a treatment, it is given at 1 kg per 1250 to 2500 L of water for 5-7 days. There is a withdrawal time of 3 days. AmproMed P for Poultry, 9.6% Oral Solution – (United States) An oral solution intended to be mixed in the water as a preventative or treatment. For prevention, it is given in the water at 0.012% for 3-5 days (8 fl oz of the product per 50 gallons of water), or as a treatment 0.024% (16 fl oz of the product in 5 gallons of water) for 3-5 days. Then, continue with 0.006% (4 fl oz of the product in 5 gallons of water) for an additional 1-2 weeks. Coxoid- (United Kingdom) Available in two sizes–112 mL or 500 mL bottle. Given in the flock’s drinking water at a rate of 28 mL per 4.5 L (1 fl oz per gallon) as a treatment for 7 days. In serious outbreaks, should be given for an additional 7 days at half strength (14 mL per 4.5 liters).

Uses/bewnefits of Amprolium Powder For Chickens

It is thiamine antagonist and due to its close structural similarity it blocks the thiamine receptors. This blockage of receptors prevents coccidia from utilizing thiamine and as a result thiamine is unavailable to coccidian (Competitive inhibition of thiamine uptake). This vitamin (thiamine pyrophosphate) is a cofactor of several decarboxylase enzymes which play role in cofactor synthesis. It is only agent which can be used in laying birds both for prevention and treatment of outbreaks. At higher doses, thiamine deficiency can occur in host but it can be prevented by addition of thiamine

Prices of Amprolium Powder For Chickens

$26.90 – $120.00

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