Baytril is an antibiotic for dogs and other animals that treats a range of bacterial infections in dogs and other animals. Typically prescribed in tablet form, it’s commonly used to treat skin infections, respiratory infections, and urinary tract infections. Baytril for dogs works by inhibiting DNA synthesis in bacteria cells, thereby killing the bacteria. If your veterinarian has prescribed Baytril for your dog, keep reading for more information about this medication’s dosage, efficacy, and side effects.

Baytril Description

Enrofloxacin is a synthetic chemotherapeutic agent from the class of the quinolone carboxylic acid derivatives. It has antibacterial activity against a broad spectrum of Gram negative and Gram positive bacteria (See Tables I and II). It is rapidly absorbed from the digestive tract, penetrating into all measured body tissues and fluids

Veterinarians frequently prescribe the antibiotic Baytril for respiratory, skin, ear and urinary tract infections and abscess and puncture wound infections in dogs. Normally Baytril, or enrofloxacin, is safe and effective but there can be side effects in some dogs. If your dog has a known sensitivity or allergy to Baytril, be sure to alert your veterinarian. Like many other drugs it can interact with other medications. If your dog is on other medication or supplements, consult with your vet about possible interactions.


The recommended dosage of Baytril is 5 to 20 mg/kg (2.27 to 9.07 mg/lb) of body weight once or twice a day.However, Baytril is also available as an injectable solution that can be administered by a veterinarian, and as Baytril Otic ear drops to treat outer ear infections.

Dosage instructions

All Baytril tablet sizes are double scored to ensure accurate dosing. The medication is best given on an empty stomach. Your veterinarian will determine the appropriate dosage size and the duration of treatment based on clinical evidence. The medication can then be given as a single daily dose or divided into two equal daily doses given 12 hours apart.

Treatment should continue for a minimum of 2 to 3 days after clinical signs cease. Severe infections may require treatment for up to 30 days.

Finally, if your dog is receiving a dose in the high end of the recommended dosage range, your vet will monitor them for the following symptoms:

  • Loss of appetite
  • Vomiting
  • Depression

Side Effects and Drug Reactions

Enrofloxacin may result in these side effects:

  • Loss of appetite
  • Vomiting
  • Diarrhea
  • Lethargy
  • Convulsions
  • Seizures in pets with CNS disorders
  • Cataracts if given long-term

Enrofloxacin may react with these drugs:

  • Aminoglycoside antibiotics
  • Antacids
  • Cephalosporin antibiotics
  • Rimadyl (and other NSAIDs)
  • Penicillin
  • Aminophylline
  • Cyclosporine
  • Nitrourantoin
  • Sucralfate
  • Theophylline


  • Drug Name: Baytril
  • Common Name: Baytril®
  • Drug Type: Fluoroquinolone antibiotic
  • Used For: Bacterial infections
  • Species: Dogs, Cats
  • Administered: Injectable, 22.7 mg and 68 mg tablets, Ear medication
  • FDA Approved: Yes

Prices of Baytril For Dogs

$34.39 – $105.99

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