Dairy cows that received a short course of anti-inflammatory medication after calving had lower metabolic stress and produced more milk than untreated cows, according to researchers, who say the regimen they tested could be adopted more easily by producers than previously studied treatment strategies.

“Dairy cows experience systemic inflammation and stress around calving, and these responses increase the risk of diseases, negatively affecting the cows’ health and performance,” said lead researcher Dr. Adrian Barragan, clinical assistant professor of veterinary and biomedical sciences in Penn State’s College of Agricultural Sciences.


For use as an aid in reducing fever and in relief of minor muscular aches and joint pains in cattle, calves, horses and foals. Readily absorbed to give animals quick relief. Also, antipyretic properties help lower body temperature and keep animals more content in extreme heat. Whenever farmers get sick, have a fever or sprain an ankle, there are countless options of aspirin or ibuprofen to take for pain relief. However, when a dairy farmer’s animal experiences pain through disease or injury, the options are extremely limited. Painkillers or analgesics are becoming more commonly accepted by producers for their food-producing animals. Administering nonsteroidal anti-inflammatory drugs (NSAID), such as flunixin, aspirin or meloxicam, to an animal is similar to giving a person acetaminophen or ibuprofen for pain relief.

Unfortunately, right now there are currently no NSAIDs specifically approved by the FDA for pain relief in lactating dairy cows. However, the Animal Medicinal Drug Use Clarification Act of 1994 (AMDUCA) permits veterinarians to prescribe extra-label uses of certain approved animal drugs and approved human drugs for animals under certain conditions.

Dosage and Administration

Mature horses and cattle: Administer orally 1 to 3 boluses two to three times daily. Lubricate bolus and administer with balling gun. Allow animals ample supply of fresh clean water after administration.

Aspirin Boluses Indications

To be used orally as an aid in reducing fever and in relief of minor muscular aches and joint pains in cattle and horses.

Uses/benefits of Cow Aspirin

Decreasing inflammation and stress could be a strategy to prevent disease in early lactation, improve the welfare and performance of dairy cows and lower disease-related costs for producers.I believe there are a number of areas where NSAIDs could benefit dairy production systems and the dairy industry in the future. The most obvious is to provide pain relief and pain management in order to address animal welfare concerns in livestock production systems,” Coetzee says. “I also believe there are unrealized economic benefits associated with the use of NSAIDs based on research we conducted with Dr. Barry Bradford’s group at Kansas State University.”

Prices of Cow Aspirin

$18.95 – $71.19

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