Incurin is a drug that is used to control urinary incontinence in dogs, specifically spayed bitches. Incurin is manufactured by Intervet Schering – Plough and contains the active ingredient Estriol, a type of oestrogen. Incurin comes in packs of 30 small, scored tablets. The dose rate is simple, starting at 1 tablet per dog per day and can be reduced if treatment is successful.    A treatment for female canine urinary incontinence that contains estriol, a naturally occurring, short-acting estrogen found in female dogs with the convenience of once-a-day dosing.


Incurin is a treatment prescribed by your veterinarian to help relieve urinary incontinence in female dogs that can occur as a result of hormonal changes after spaying. It comes in a tablet form, so you can easily hide it in a pill pocket and give it as a tasty treat, or disguise it in your dog’s favorite wet food.
Incurin Tablets are an effective treatment for the control of estrogen-responsive urinary incontinence in dogs that have undergone surgical removal of the ovaries and uterus (ovariohysterectomy). This medication has been used effectively worldwide for more than 12 years. Incurin Tablets require a prescription from your veterinarian.

Dosage and Administration

The dose of INCURIN® Tablets is not dependent upon body weight. All dogs should receive an initial dose of 2 mg INCURIN® Tablets (2 tablets) orally once per day for a minimum of 14 days. After urinary incontinence is controlled, the lowest effective daily dose of INCURIN® Tablets should be determined by decreasing the dose in a step-wise manner from 2 mg once daily (2 tablets) to 1 mg once daily (1 tablet), then 0.5 mg once daily (1/2 tablet) depending upon the response of the individual dog. There should be a minimum of 7 days between each dose adjustment. After the lowest daily dose that controls urinary incontinence is identified, the dose may be decreased further by administering once every two days. Dogs should not receive more than 2 mg INCURIN® Tablets per day (2 tablets). If the dog does not respond to 2 mg of INCURIN® Tablets per day, the diagnosis should be re-assessed.

Features and Benefits

  • Proven effective in reducing or eliminating urinary incontinence1
  • 93% of dogs treated were improved or continent by 6 weeks1
  • Convenient, once-a-day dosing
  • One simple starting dose for all female dogs and just 1 tablet size to stock
  • Titrated to the lowest effective dose

Side Effects

  • Incurin can have side effects at high doses.
  • Side effects are most likely to occur if animals are receiving >2 tablets per day.
  • Side effects from Incurin are related to the oestrogen increasing female traits.
  • Incurin can cause a swollen vulva and increased attractiveness to males.
  • Incurin can cause an increase in size of mammary tissue.
  • Side effects are reversible if the dose of Incurin is lowered.
  • Incurin should not be used in pregnant animals.
  • Incurin should not be used in intact bitches.
  • Incurin should not be used in animals less than 1 year old.
  • In very rare cases vaginal bleeding and hair loss can be seen.


Human Warnings: Not for human use. Keep out of the reach of children. Women who are of child-bearing age or those who are breastfeeding should use caution when administering INCURIN® Tablets. Wash your hands with soap and water after administration to avoid exposure to the drug. Consult a physician in case of accidental ingestion by humans.

Animal Warnings: Some estrogens have been associated with bone marrow changes and an increased risk of mammary tumors. However, target animal safety study results and foreign post-market pharmacovigilance data for INCURIN® Tablets have shown that estriol-treated dogs are at low risk for developing these conditions.

Prices of Incurin For Dogs

$18.54 – $29.76

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