Infectious Bronchitis Vaccine Poultry

Infectious bronchitis (IB) is caused by a specific virus known as infectious bronchitis virus (IBV), a member of the Coronavirus genus within the Coronaviridae. Infectious bronchitis is an acute and highly contagious respiratory disease of chickens. It has worldwide distribution.

Several different serotypes of IB virus are known to exist. Although it does indeed cause respiratory disease it also replicates at many non-respiratory epithelial surface, where it may cause pathology e.g. kidney, gonads. Strains of the virus vary in the extent to which they cause pathology in non-respiratory organs.To control the disease live and inactivated vaccines of various serotypes are in use.


Infectious bronchitis virus (IBV) is an avian gammacoronavirus that only causes disease in chickens, although the virus has also been found in pheasants and peafowl, which may be subclinically infected. The virus is worldwide in distribution, and there are many antigenic types that can cocirculate in a given region. Some IBV types are widespread, whereas others are regional.

IBV is shed by infected chickens in respiratory discharges and feces, and it can be spread by aerosol, ingestion of contaminated feed and water, and contact with contaminated equipment and clothing. Naturally infected chickens and those vaccinated with live IBV may shed virus intermittently for up to 20 weeks after infection. The incubation period is generally 24–48 hours, with the peak in excretion of virus from the respiratory tract lasting 3–5 days after infection.

Vaccine strains

If variant IB strains are not present, or if they are present but fall under the protectotype of the Massachusetts serotype, then a program based on this serotype can be used. If not, broader protection can be obtained by including vaccines belonging to other serotypes (such as vaccines containing serotypes 4/91) in the program.

It is not always obligatory to include a live and inactivated vaccine of the same type in the program. Some live vaccine viruses will be effective in priming birds for heterologous IB components in the inactivated vaccine and a cross reaction will occur resulting in stimulation of immunity to heterologous IBVs and therefore providing cross protection. This is for example the case after the use of vaccines with serotype 4/91. When followed by an inactivated vaccine containing a strain of the Massachusetts serotype, a cross reaction will result in high levels of neutralizing antibodies not only against the Massachusetts serotype but also against the 4/91 serotype, and against some other IB serotypes as well.

Features/ administration

CompositionEach dose contains live Infectious Bronchitis virus, 793B type, at least 103.5EID50.
IndicationsActive immunization of chickens against Infectious Bronchitis.
Indications for useUse by instructions of a veterinarian.
Use immediately after reconstitution with antiseptic or disinfectant free drinking water.
and dosage
• Prepare for each 1,000 doses 100-300 ml of non chlorinated water.
• Add the reconstituted vaccine to the adequate volume of spraying water, immediately prior to use, and mix well.
• The ventilation system of the poultry house should be inoperative during the spray/aerosol administration.
• Direct the stream from the sprayer over the heads of the birds.
• Droplets of 100-300μm diameter are ideal as they facilitate even coverage of birds.
Drinking water:
• Make sure that drinking water is free of any traces of disinfectants.
• Deprive the birds of drinking water two hours before vaccination.
• Prepare adequate volume of drinking water to be consumed within one to two hours.
• Protect the dissolved vaccine from chlorine by adding BIOVAC’S Blue Neutrachlor® (following the instructions) or skim milk powder (50g/20L) or skim milk (0.5L/20L) to drinking water to be consumed within one to two hours.
• Stir well after mixing and allow solution to stand for 20 min. before adding the vaccine.
• Mix well the reconstituted vaccine in the final volume of disinfectant-free drinking water.
• Let the birds consume all the vaccine-water volume before renewing water supply.
Ocular route:
The vaccine should be dissolved in physiological saline solution (usually 40 ml per 1,000 doses) and administered by means of a standardized dropper. Administer one drop (0.04ml) of vaccine into the open eye of each bird.
Comments• Vaccinate healthy birds only.
• Use entire contents of the vial when first opened.
• Destroy unused contents and decontaminate empty vials before discarding them.
• Keep vaccination records including vaccine batch number.
ContraindicationsFuture layers and breeders should not be vaccinated before 3 weeks of age.
Withdrawal periodNill
StorageStore at 2ºC-8ºC, protected from direct sunlight.
PresentationEach box contains 10 or 20 vials of 1,000, 2,500 or 5,000 doses.

Prices of Infectious Bronchitis Vaccine Poultry

$10.00 – $65.00

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