Penicillin G is a natural penicillin and is available in several different salt forms. Natural penicillins remain the drugs of choice for a variety of bacteria, including group A beta-hemolytic streptococci, many gram positive anaerobes, spirochetes, gram negative aerobic cocci, and some gram negative aerobic bacilli. Generally, if a bacteria is susceptible to a natural penicillin, either penicillin G or V is preferred for treating that infection as long as adequate penetration of the drug to the site of the infection occurs and the patient is not hypersensitive to penicillins. Penicillin is mainly of benefit only for cases where birds are infected with Pasteurella spp. and some gram-positive organisms. Pasteurella spp. are commonly found in the oral cavity of dogs, cats and other canine and feline predators. Storage/Stability: Penicillin G sodium and potassium should be protected from moisture to prevent hydrolysis of the compounds.
Penicillin G potassium tablets and powder for oral solution should be stored at room temperature in tight containers; avoid exposure to excessive heat. After reconstituting, the oral powder for solution should be stored from 2-8°C (refrigerated) and discarded after 14 days. Penicillin G sodium and potassium powder for injection can be stored at room temperature (15-30°C). After reconstituting, the injectable solution is stable for 7 days when kept refrigerated (2-8°C) and for 24 hours at room temperature. Penicillin G procaine should be stored at 2-8°C; avoid freezing. Benzathine penicillin G should be stored at 2-8°C.
Penicillins are beta-lactam antibiotics derived from 6-aminopenicillanic acid. The natural penicillins include sodium and potassium salts of benzyl penicillins. Semisynthetic penicillins possess properties that improve upon deficiencies of natural penicillins, including wider antimicrobial spectrum and decreased susceptibility to degradation by gastric acids and beta-lactamase enzymes.
Is a semisynthetic derivative of penicillin and an analog of ampicillin that displays a broad spectrum of antibacterial activity (bactericidal) against many gram-positive and gram-negative organisms, inactivated by beta-lactamases. Amoxicillin is absorbed better and has more rapid action and greater resistance to the gastric acid than ampicillin. Amoxicillin is stable in the presence of gastric acid and is a drug of choice within the class because of better oral bioavailability.
Uses/benefits of Injectable Penicillin For Chickens
Beta-lactam antibiotics lyse bacteria by binding to cytoplasmatic membrane enzymes (penicillin-binding proteins). This inhibits a step in peptidoglican synthesis that is crucial for cell wall formation. All members of the family have a beta-lactam ring and a carboxyl group resulting in similarities in the pharmacokinetics and mechanism of action of the group members.
|Species||Indications for use||Penicillin|
g / ton
|Lb of Penicillin 100 Premix|
|Swine||For increased rate of weight gain and improved feed efficiency.||10 – 50||0.167 – 0.834|
|Chickens||For increased rate of weight gain and improved feed efficiency.||2.4 – 50||0.04 – 0.834|
|Turkeys||For increased rate of weight gain and improved feed efficiency.||2.4 – 50||0.04 – 0.834|
|Pheasants||For increased rate of weight gain and improved feed efficiency.||2.4 – 50||0.04 – 0.834|
|Quail||For increased rate of weight gain and improved feed efficiency.Limitation: Not for use in quail over 5 weeks of age.||5 – 20||0.0834 – 0.333|
Prices of Injectable Penicillin For Chickens
$25.24 – $45.54