Metronidazole For Dogs

Metronidazole has been used for many years in therapeutic management of trichomoniasis, giardiasis, and amebiasis. It is active against obligate anaerobic bacteria. It is not active against facultative anaerobes, obligate aerobes, or microaerophilic bacteria other than Campylobacter fetus.

At concentrations readily attained in serum after PO or parenteral administration, metronidazole is active against Bacteroides fragilisB melaninogenicusFusobacterium spp, and Clostridium perfringens and other Clostridium spp. It is generally less active against nonsporeforming, gram-positive bacilli such as ActinomycesPropionibacteriumBifidobacterium, and Eubacterium spp. Metronidazole is also somewhat less active against gram-positive cocci such as Peptostreptococcus and Peptococcus spp, but the less sensitive strains are usually not obligate anaerobes

Metronidazole is a prescription antibiotic used to treat many types of infections in humans. It works by stopping bacteria or parasites from growing and multiplying. Metronidazole can also reach the central nervous system and bones, making it helpful for brain, spinal cord, and bone infections. 


Metronidazole (also known by the brand names Flagyl, Metizol, Protostat, Metrogel) is a strong antibiotic primarily used as an antidiarrheal to treat inflammation of the large intestine. It’s also used for other illnesses and conditions in dogs, cats, and horses, as well as to treat bacterial infections in humans. It is often prescribed in combination with other antibiotics.

Metronidazole is a prescription-only medication that can be taken orally or used topically, depending on the illness being treated. The U.S. Food and Drug Administration has not yet approved metronidazole for veterinary use (it is approved for human use), but veterinarians often prescribe it for their canine and feline patients. Many of the parasites and bacteria that make us sick also affect our pets, and this is one human medication that can often help them.

Features of Metronidazole For Dogs

Metronidazole is available as a capsule, tablet, and liquid suspension. It may also be compounded (made) into a formulation (called metronidazole benzoate) that tastes less bitter and is easier to administer to cats. An injectable form is also available that your veterinarian will administer at your veterinary hospital. Metronidazole should be given by mouth with food. Liquid forms must be shaken well before use. Metronidazole is very bitter, so take care not to crush these tablets as it will be difficult to administer to your pet.

Follow the dosing instructions provided by your veterinarian. If you have difficulty administering the medication, contact your veterinary clinic for advice. This medication should take effect within 1 to 2 hours, and while effects may not be visibly noticed immediately, but gradual improvements are usually noticable after a few days.

Uses/benefits of Metronidazole

Metronidazole treats bacterial infections and some parasites, so it is prescribed to treat a variety of conditions and to relieve their symptoms. It’s often used to treat:

  • Giardia (and other parasites)
  • Inflammatory Bowel Disease (IBD)
  • Oral and dental infections
  • Other bacterial infections that cause diarrhea or sepsis, abscesses, meningitis

side effects of metronidazole in dogs

Metronidazole can lower the amount of healthy gut bacteria in dogs, which in turn may cause more diarrhea. Its bitter flavor may also cause more drooling than usual.  Other common side effects of metronidazole are: 

  • Nausea/vomiting
  • Gagging
  • Feeling more tired than usual
  • Lower appetite
  • Discolored urine
  • Fever


  • Dogs and cats: Symptoms of overdose of metronidazole include the gastrointestinal signs (anorexia, vomiting) and neurologic signs including depression, ataxia, disorientation, head tilt, tremors, bradycardia, rigidity, stiffness, and seizures. Neurologic signs may occur due to acute overdose although they more commonly are seen in animals that are on long-term moderate or high doses (oral doses greater than 66 mg/kg/day). Signs of chronic toxicity often begin seven to 12 days following the start of treatment. After the drug is discontinued, it may be several days to two weeks before these neurologic signs begin to diminish.
  • No specific information was found in the literature about overdose in the horse

Prices of Metronidazole For Dogs

$98.4 – $136.8

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