Nuflor is used for the treatment of acute outbreaks of respiratory disease caused by strains of Actinobacillus pleuropneumoniae and Pasteurella multocida susceptible to florfenicol. Such diseases might include pneumonia, lung consolidation, lung, nasal and joint infections and meningitis. NUFLOR Injectable Solution is a solution of the synthetic antibiotic florfenicol. Each milliliter of sterile NUFLOR Injectable Solution contains 300 mg of florfenicol, 250 mg N-Methyl-2-pyrrolidone, 150 mg propylene glycol, and polyethylene glycol qs. The chemical name for florfenicol is 2,2-Dichloro-N-[1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl] acetamide.


Florfenicol is a broad-spectrum synthetic antibiotic effective against most Gram positive and Gram negative bacteria isolated from domestic animals. In cattle, Nuflor is indicated in diseases caused by florfenicol susceptible bacteria. Nuflor is indicated for the prevention and treatment of respiratory tract infections due to Mannheimia haemolytica, Pasteurella multocida and Histophilus somni. The presence of the disease in the herd should be established before preventive treatment. In sheep, Nuflor is indicated for the treatment of ovine respiratory tract infections due to Mannheimia haemolytica and Pasteurella multocida susceptible to florfenicol. 

Features and Benefits of Nuflor For Foot Rot

Injectable Solution controls all three major bacterial causes of bovine respiratory disease (BRD) and even treats foot rot.
Unique, fast-acting, long-lasting antibiotic for treatment of bovine respiratory disease, foot rot and control of respiratory disease in cattle at high risk of developing bovine respiratory disease.

  • Kills two major bacteria that cause BRD: Mannheimia haemolytica and Histophilus somni. Begins killing within 30 minutes and eliminates 99.9% of those bacteria within 24 hours. Continues to kill for 68 hours and remains inhibitory through 96 hours.1
  • Inhibits the third major bacterial cause of BRD: Pasteurella multocida.2
  • Effective, versatile, broad spectrum therapy in the hospital and on arrival of cattle at risk of developing BRD.
  • Lowers risk with high-risk cattle – treat on arrival.
  • Fewer repulls and retreatments.
  • Easy to use, requires no mixing or reformulation and isn’t contraindicated in automatic injection equipment.


NUFLOR Injectable Solution is indicated for treatment of bovine respiratory disease (BRD), associated with Mannheimia (Pasteurella) haemolytica, Pasteurella multocida, and Histophilus somni, and for the treatment of bovine interdigital phlegmon (foot rot, acute interdigital necrobacillosis, infectious pododermatitis) associated with Fusobacterium necrophorum and Bacteroides melaninogenicus. Also, it is indicated for the control of respiratory disease in cattle at high risk of developing BRD associated with Mannheimia (Pasteurella) haemolytica, Pasteurella multocida, and Histophilus somni.

Dosage / administration

 For treatment of bovine respiratory disease (BRD) and bovine interdigital phlegmon (foot rot): NUFLOR Injectable Solution should be administered by intramuscular injection to cattle at a dose rate of 20 mg/kg body weight (3 mL/100 lbs). A second dose should be administered 48 hours later. Alternatively, NUFLOR Injectable Solution can be administered by a single subcutaneous (SC) injection to cattle at a dose rate of 40 mg/kg body weight (6 mL/100 lbs). Do not administer more than 10 mL at each site. The injection should be given only in the neck.


  • Do not use in calves to be processed for veal
  • Store at or below 25°C (77°F)

Prices of Nuflor For Foot Rot

$99.95 – $179.14

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