Oxytetracycline is a highly active broad-spectrum antibiotic that works by inhibiting protein synthesis. Other similar drugs include Chlortetracycline, Tetracycline, and Doxycycline. Oxytetracycline has activity against gram-positive and gram-negative bacteria, including some anaerobes. It is also active against Chlamydia, Mycoplasmas, and some protozoa, and several rickettsiae. Specific bacteria within the tetracycline’s activity range include Escherichia coli, Klebsiella spp, Pasteurella spp, Salmonella spp, Staphylococcus spp, and Streptococcus spp.


Oxytetracycline can be given in drinking water and feed, or SC or IM. With IM administration there is a risk it can cause muscle irritation or necrosis. After IM administration of oxytetracycline (not long-acting), peak levels may occur in 30 minutes to several hours, depending on the volume and site of injection. Oxytetracycline is readily absorbed after oral administration in fasting birds. Bioavialabilities are approximately 60-80%. The pres­ence of products or foods containing Al, Ca, Mg, or Fe reduce or alter the absorption of the drug. If given in drinking water, it should simultaneously be given in feed as well. Storage/Stability: Unless otherwise directed by the manufacturer, oxytetracycline HCl and oxytetracycline products should be stored in tight, light-resistant con­tainers at temperatures of less than 40°C (104°) and preferably at room temperature (15-30°C); avoid freezing. Note that if this drug is used after its expiration date, it becomes nephrotoxic.

Uses/benefits of Oxytetracycline For Ducks

Tetracyclines generally act as bacteriostatic antibiotics. Broad spectrum antibiotics with activity against Gram-positive and Gram-negative bacteria. Resistance is widespread. The tetracyclines are a closely related group of antibiotics with comparable pharmacological properties but different pharmacokinetic characteristics.

 Tetracyclines inhibit bacterial protein synthesis. Their site of action is the bacerial ribosome – 30 S subunit, thereby preventing binding to those ribosomes of aminoacyl transfer-RNA. Active transport of the drug into the bacterial cell must occur in order for the drug to be effective. Doxycycline enters the cell by passive diffusion.

1. Absorption is almost complete
2. Tissue penetration is good
3. Elimination is slower


High dosages or chronic administration may delay bone growth and healing in young poultry. Tetracyclines in high levels can exert an antianabolic effect which can cause an increase in BUN and/or hepatotoxicity, particularly in patients with preexisting renal dysfunction. As renal function deteriorates secondary to drug accumulation, this effect may be exacer­bated.


For the control of the following poultry diseases caused by organisms susceptible to oxytetracycline: Add the following amount to two gallons of stock solution when proportioner is set to meter at the rate of one ounce per gallon.

Infectious synovitis caused by Mycoplasma synoviae.200-400 mg/gal5-10
Chronic respiratory disease (CRD) and air sac infection caused by Mycoplasma gallisepticum and Escherichia coli.400-800 mg/gal10-20
Fowl cholera caused by Pasteurella multocida.400-800 mg/gal10-20
Hexamitiasis caused by Hexamita meleagridis.200-400 mg/gal5-10
Infectious synovitis caused by Mycoplasma synoviae.400 mg/gal10
Growing Turkeys – Complicating bacterial organisms associated with bluecomb (transmissible enteritis, coronaviral enteritis).25 mg/lb body weight dailyvaries with age & water consumption (1 packet will treat 400 pounds of turkeys.)

Prices of Oxytetracycline For Ducks

$16.00 – $147.00

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